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Case Studies using
bioinstrument Manager
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Codes to the left of the case study description correspond to the services and products we offer.
- BIO-- bioinstrument Manager
- PM-- Project Management
- DB-- Data Management and Databases
- QA-- Quality
- SE-- Embedded/ Scientific Programming
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For service-based case studies, go to
Services Case Studies.
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Case Study Descriptions |
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BIO
PM
DB
QA
SE |
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Remote, Near Real-time proteomics analysis for ISB
The
Institute for Systems Biology (ISB)
(http://www.systemsbiology.org) needed more
information than a proprietary LC/MS program was providing. The
challenge was to display real-time data charting and make the
process accessible from remote locations. Userspace's solution
was to write LC/MS device protocols and access the LC/MS through
BioInstrument Manager, incorporate a real-time graphical peakpoint
display of the data streaming from the instrument, and securely
enable access to the instrument through BioInstrument Manager through
the Web. The results are ISB employees can...
- Pause an experiment.
- Receive SMS (cell phone) error and status messages on their cell phone or
PDA during a sample's run, when a QA run fails.
- Securely see an experiment's results from workstations within the company or
off-site.
- Watch a real-time graphical display of peak points during an experiment.
- Replay or expand any portion of the peak point display they desire.
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BIO
PM
DB
QA
SE |
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Automated, batch labeling of vials
The Institute for
Systems Biology (ISB)(http://www.systemsbiology.org)
needed to track its samples more efficiently. The challenge was to label vials
and store the information for later use. Userspace's solution
was to build a labeler, integrate the labeler and barcode scanner
into BioInstrument Manager, and create a process for making batches
and storing the information in ISB's database. The results are
ISB employees can...
- Create a unique batch of labeled vials for an experiment or sample set.
- Store the scanned vial information into a data source.
- Take the vial information and link it to clinical data about the samples
in ISB's proprietary database.
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BIO
PM
DB
QA
SE |
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Robust lab sample receipt-to-billing management and reporting system
HematoLogics, Inc.
( http://www.hematologics.com)
needed a more robust method of tracking its samples through the
lab work, medical analysis and billing phases. The challenge
was maintaining existing data and reports while providing a more
complete automated solution that is securely accessible on-line.
Userspace's solution was to convert the existing MS Access
database and business rules to an N-tier architecture, utilizing MS
SQL Server as the database and BioInstrument Manager as the interface
and process management solution. The results are HematoLogics'
employees can use their Web browser to...
- Track a patient's sample from its receipt in the office through lab work,
analysis and reporting, and outsourcing to other labs and billing
agencies.
- Always know where a sample is through the workflow process.
- Prepare lab analysis and interpretations on-line.
- Automatically create customized graphical PDF reports explaining the lab results.
- Send reports to patients' physicians and billing agencies.
- Locate and display on-line specimen information and reports for roughly
20,000 patients.
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BIO
PM
DB
QA
SE |
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Automated flow cytometry tetramer analysis and reporting
The Benaroya Research Institute at
Virginia Mason (http://www.benaroyaresearch.org/) needed
to provide consistent analysis and reporting of Type I diabetes
clinical trial samples from the Immune Tolerance Network
(http://www.immunetolerance.org/).
The challenge was to provide a quick, clinical sound method
for standardized analysis of flow cytometry data and reporting of
results. Using BioInstrument Manager, Userspace’s solution
was to develop an automated process that algorithmically separated
cells into distinct regions, graphed the steps and scored the results
for tetramer positive findings. The results are lab and
physician personnel at BRI can…
- Have consistent, algorithmically-based analysis results for every run,
regardless of the operator.
- Process 2-200 FCS files with an average time of 30 seconds per group of four
(4).
- Use an intuitive GUI to select FCS files and group and regroup them
based on tetramer and peptide parameters.
- Analyze the FCS files based on a threshold the operator sets for each run.
- View results of previous runs, including automation steps, graphs and
reports.
- Automatically generate graphical PDF reports for a run.
- Export the results to JPEG, Excel or PDF formats.
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